1999

In 1999, three new original Cartoon Network cartoons premiere, Ed, Edd n Eddy, Mike, Lu & Og and Courage the Cowardly Dog. Cow and Chicken ends this year, being the first of the original Cartoon Network cartoons to do so.

4

 * Cartoon Network's 9th original series, Ed, Edd n Eddy, premieres with the episode, "The Ed-Touchables/Nagged to Ed".

8

 * The 4th and final season of Cow and Chicken premieres with the episode, "Invisible Cow/Monster in the Closet/I Am Hairstylist".

20

 * Greatest Cartoon Countdown aired, from 2:00 PM to 10:00 PM.

11

 * The weekly programming block, Cartoon Cartoon Fridays, premieres.

25

 * The 2nd season of The Powerpuff Girls premiered with the episode, "Stuck Up, Up and Away/Schoolhouse Rocked".

2

 * The 2nd season of Johnny Bravo premieres with the episode, "Bikini Space Planet/Moby Jerk/A Gel For Johnny".

9

 * Moltar hosts Toonami for the last time.

10

 * A late night Toonami programming block, Midnight Run, premieres from Midnight to 5:00am.
 * The new host of Toonami, TOM, is introduced during the first Midnight Run broadcast. (technically at 11:55pm on July 9th)

22

 * Cartoon Network's 10th original series, I Am Weasel, premieres as a standalone series, after airing as a segment of Cow and Chicken from 1997 to 1999.

24

 * The final season of Cow and Chicken concludes with the episode, "The Cow and Chicken Blues/The Ballad of Cow and Chicken/I Are Good Salesman".

20-22

 * Cartoon Network airs its 3rd annual Cartoon Cartoon Weekend.

23

 * Cartoon Network France, Spain and CEE feeds are separated from the UK feed.

12

 * Cartoon Network's 11th original series, Mike, Lu & Og, premieres with the episode, "Sultans of Swat/Tea for Three".
 * Cartoon Network's 12th original series, Courage the Cowardly Dog, premieres with the episode, "A Night at the Katz Motel/Cajun Granny Stew".

10

 * The Dexter's Laboratory animated film, Ego Trip, premieres. It is intended to be the series finale.

11

 * Movie Marathon aired.

18-19

 * Cartoon Network airs a 2-day Looney Tunes marathon in celebration of New Years, titled the Mil-Looney-Um.

30

 * The early morning programming block, Cartoon-A-Doodle-Doo, airs for the final time.
 * Cartoon Network airs a 36 hour Jetsons marathon in celebration of New Years, titled The Jetsons Millennium Marathon.