The Big Game XXVIII: Road Runner vs. Coyote

The Big Game XXVIII: Road Runner vs. Coyote was a 4-hour marathon that aired on Cartoon Network on Saturday, January 29, 2000, from 6:00 PM to 10:00 PM, with the first hour consisting of a pre-game show that featured analysis by experts Jerry Glanville, Nick Buoniconti, Cris Collinsworth and Len Dawson (returning via their duties as hosts of HBO's Inside the NFL) as well as narration by Harry Kalas. The marathon featured 18 Looney Tunes shorts starring the Road Runner and Wile E. Coyote as well as play-by-play and color commentary from Pat Summerall and John Madden during commercials. The marathon also featured segments with Scott Hamilton and Bubba Smith providing sideline reports from Chuck Jones Stadium, and Jack Hanna offering a zoological breakdown of the two competitors. The marathon was also aired the following day (Super Bowl Sunday) from 1:00 PM to 5:00 PM.

During the "Halftime Show" segment, there is a scene in the control room with Moltar and Fred Jones talking about last year's Scooby-Doo Project.

This was the third in a series of four Super Bowl spoof marathons that aired annually on Cartoon Network from 1998-2001. These marathons came to be known as "The Big Game"; however, only the final two actually featured this moniker.

The game itself used clips from the following Road Runner cartoons:
 * Hopalong Casualty (first quarter)
 * Zoom at the Top (second quarter)
 * Fastest with the Mostest (third quarter)
 * To Beep or Not to Beep (fourth quarter)